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Local CpG density affects the trajectory and variance of age-associated DNA methylation changes.
Higham, Jonathan; Kerr, Lyndsay; Zhang, Qian; Walker, Rosie M; Harris, Sarah E; Howard, David M; Hawkins, Emma L; Sandu, Anca-Larisa; Steele, J Douglas; Waiter, Gordon D; Murray, Alison D; Evans, Kathryn L; McIntosh, Andrew M; Visscher, Peter M; Deary, Ian J; Cox, Simon R; Sproul, Duncan.
Afiliación
  • Higham J; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Kerr L; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Zhang Q; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia.
  • Walker RM; Present address: Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK.
  • Harris SE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Howard DM; Present address: School of Psychology, University of Exeter, Edinburgh, UK.
  • Hawkins EL; Department of Psychology, Lothian Birth Cohorts Group, University of Edinburgh, Edinburgh, UK.
  • Sandu AL; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Steele JD; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
  • Waiter GD; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
  • Murray AD; Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
  • Evans KL; Division of Imaging Science and Technology, Medical School, University of Dundee, Dundee, UK.
  • McIntosh AM; Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
  • Visscher PM; Aberdeen Biomedical Imaging Centre, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
  • Deary IJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Cox SR; Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
  • Sproul D; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia.
Genome Biol ; 23(1): 216, 2022 10 17.
Article en En | MEDLINE | ID: mdl-36253871
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metilación de ADN / Epigénesis Genética Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metilación de ADN / Epigénesis Genética Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido