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Iridoids and sesquiterpenoids from Valeriana officinalis and their bioactivities.
Shi, Dao-Qun; Liu, Jia-Jin; Feng, Yu-Mei; Zhou, Yan; Liao, Cai-Cen; Liu, Dan; Li, Rong-Tao; Li, Hong-Mei.
Afiliación
  • Shi DQ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China. Electronic address: 1730658315@qq.com.
  • Liu JJ; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China.
  • Feng YM; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China.
  • Zhou Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China.
  • Liao CC; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China.
  • Liu D; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China.
  • Li RT; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China. Electronic address: rongtaolikm@163.com.
  • Li HM; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, PR China. Electronic address: lihongmei0823@163.com.
Phytochemistry ; 205: 113478, 2023 Jan.
Article en En | MEDLINE | ID: mdl-36273591
Twenty-six iridoids, including six undescribed ones (iridoidvols A-F) and an undescribed natural one, along with ten known sesquiterpenoids were isolated from the roots and rhizomes of Valeriana officinalis. Structurally, iridoidvol A is the first example of iridoid with sesquiterpenoid acid ester. In addition, all of the isolates were evaluated for anti-inflammatory and anti-influenza virus activities. Among them, isovaltrate isovaleroyloxyhydrin exhibited a significant inhibitory effect on NO production with an IC50 value of 19.00 µM.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Valeriana Idioma: En Revista: Phytochemistry Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Valeriana Idioma: En Revista: Phytochemistry Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido