Cerebrospinal Fluid Polymerase Chain Reaction in the Diagnosis of Neonatal Bacterial Meningitis: A Single-Center Experience From Vietnam.
Indian Pediatr
; 59(12): 943-945, 2022 12 15.
Article
en En
| MEDLINE
| ID: mdl-36333894
ABSTRACT
OBJECTIVE:
To compare the performance of cerebrospinal fluid (CSF) polymerase chain reaction (PCR) with bacterial culture for the diagnosis of neonatal bacterial meningitis (NBM).METHOD:
The CSF analysis of neonate with confirmed bacterial meningitis was performed with PCR and bacterial culture, and results were compared.RESULT:
Among 24 neonates, the pathogens Identified included E. coli K1, GBS, Streptococcus pneumoniae and Listeria. PCR identified 20 (83.3%) pathogens, and culture 4 (16.7%) pathogens. Prior antibiotics were administered to 20 (83.3%) neonates in whom PCR identified 17 (85%) and culture 3 (15%) pathogens.CONCLUSION:
CSF PCR had a higher yield of pathogens than CSF culture in confirmed neonatal bacterial meningitis with a high rate of prior antibiotic therapy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Meningitis Bacterianas
/
Enfermedades del Recién Nacido
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
Indian Pediatr
Año:
2022
Tipo del documento:
Article
País de afiliación:
Vietnam