Inhibition of ABL1 by tyrosine kinase inhibitors leads to a downregulation of MLH1 by Hsp70-mediated lysosomal protein degradation.

Daniels, Hannah G; Knicely, Breanna G; Miller, Anna Kristin; Thompson, Ana; Plattner, Rina; Goellner, Eva M

Daniels, Hannah G; Knicely, Breanna G; Miller, Anna Kristin; Thompson, Ana; Plattner, Rina; Goellner, Eva M.

Afiliación

Daniels HG; University of Kentucky, College of Medicine Department of Toxicology and Cancer Biology, Lexington, KY, United States.
Knicely BG; University of Kentucky, College of Medicine Department of Toxicology and Cancer Biology, Lexington, KY, United States.
Miller AK; University of Kentucky, College of Medicine Department of Toxicology and Cancer Biology, Lexington, KY, United States.
Thompson A; Berea College, Berea, KY, United States.
Plattner R; University of Kentucky Markey Cancer Center, Lexington, KY, United States.
Goellner EM; University of Kentucky Markey Cancer Center, Lexington, KY, United States.

Front Genet ; 13: 940073, 2022.

Article en En | MEDLINE | ID: mdl-36338985

Palabras clave

DNA repair; Hsp70; lysosome; mismatch repair; nilotinib dasatinib

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Genet Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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