Photoredox-Ni Dual Catalysis: Chelation-Free Hydroacylation of Terminal Alkynes.
Org Lett
; 24(45): 8435-8440, 2022 11 18.
Article
en En
| MEDLINE
| ID: mdl-36342240
ABSTRACT
Hydroacylation of alkynes is undoubtedly the simplest and most atom-efficient approach for the synthesis of enones with diverse synthetic applications. Despite significant progress in hydroacylations, no hydroacylations exist that make use of aldehydes without a chelating group, especially when combined with terminal alkynes. Here we report a synergistic nickel-photocatalytic system that allows for the highly regio- and stereoselective hydroacylation of unactivated aldehydes and alkynes in milder conditions without the use of chelating groups.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aldehídos
/
Alquinos
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2022
Tipo del documento:
Article
País de afiliación:
India