The modulatory effects of two bioflavonoids, quercetin and thymoquinone on the expression levels of DNA damage and repair genes in human breast, lung and prostate cancer cell lines.

Karimian, Ansar; Majidinia, Maryam; Moliani, Afshin; Alemi, Forough; Asemi, Zatollah; Yousefi, Bahman; Fazlollahpour Naghibi, Andarz

Karimian, Ansar; Majidinia, Maryam; Moliani, Afshin; Alemi, Forough; Asemi, Zatollah; Yousefi, Bahman; Fazlollahpour Naghibi, Andarz.

Afiliación

Karimian A; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Majidinia M; Solid Tumor Research Centre, Urmia University Medical Sciences, Urmia, Iran.
Moliani A; Isfahan Medical Students Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Alemi F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Asemi Z; Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
Yousefi B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: yousefib@tbzmed.ac.ir.
Fazlollahpour Naghibi A; Solid Tumor Research Centre, Urmia University Medical Sciences, Urmia, Iran; Faculty of Medicine, Islamic Azad University, Sari Branch, Sari, Iran. Electronic address: Andarz.fpr@gmail.com.

Pathol Res Pract ; 240: 154143, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36347210

Asunto(s)

Neoplasias de la Próstata; Quercetina; Masculino; Humanos; Quercetina/farmacología; Flavonoides/farmacología; Proteína p53 Supresora de Tumor/metabolismo; 8-Hidroxi-2'-Desoxicoguanosina; Daño del ADN; Neoplasias de la Próstata/tratamiento farmacológico; Neoplasias de la Próstata/genética; Neoplasias de la Próstata/metabolismo; Células MCF-7; Pulmón/metabolismo; Línea Celular Tumoral; Apoptosis; Proteína 1 de Reparación por Escisión del Grupo de Complementación Cruzada de las Lesiones por Rayos X/genética

Palabras clave

DNA damage; DNA repair; P53; Quercetin; Thymoquinone

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Quercetina Límite: Humans / Male Idioma: En Revista: Pathol Res Pract Año: 2022 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Alemania

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