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Pharmacogenetic variability and the probability of site of action target attainment during tuberculosis meningitis treatment: A physiologically based pharmacokinetic modeling and simulations study.
Mehta, Krina; Narayanan, Navaneeth; Heysell, Scott K; Bisson, Gregory P; Subbian, Selvakumar; Kurepina, Natalia; Kreiswirth, Barry N; Vinnard, Christopher.
Afiliación
  • Mehta K; Leiden University, Leiden, the Netherlands. Electronic address: k.m.mehta@lacdr.leidenuniv.nl.
  • Narayanan N; Rutgers University, Ernest Mario School of Pharmacy, Piscataway, NJ, USA.
  • Heysell SK; University of Virginia, Division of Infectious Diseases and International Health, Charlottesville, VA, USA.
  • Bisson GP; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
  • Subbian S; Public Health Research Institute, New Jersey Medical School, Newark, NJ, USA.
  • Kurepina N; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
  • Kreiswirth BN; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
  • Vinnard C; Rutgers University, New Jersey Medical School, Newark, NJ, USA.
Tuberculosis (Edinb) ; 137: 102271, 2022 12.
Article en En | MEDLINE | ID: mdl-36375279
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arilamina N-Acetiltransferasa / Tuberculosis Meníngea / Mycobacterium tuberculosis Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Tuberculosis (Edinb) Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arilamina N-Acetiltransferasa / Tuberculosis Meníngea / Mycobacterium tuberculosis Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Tuberculosis (Edinb) Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido