Analysis of thermally driven structural changes, genome release, disassembly, and aggregation of recombinant AAV by CDMS.

Barnes, Lauren F; Draper, Benjamin E; Jarrold, Martin F

Barnes, Lauren F; Draper, Benjamin E; Jarrold, Martin F.

Afiliación

Barnes LF; Chemistry Department, Indiana University, 800 E Kirkwood Avenue, Bloomington, IN 47405, USA.
Draper BE; Megadalton Solutions, Inc., 3750 E Bluebird Ln, Bloomington, IN 47401, USA.
Jarrold MF; Chemistry Department, Indiana University, 800 E Kirkwood Avenue, Bloomington, IN 47405, USA.

Mol Ther Methods Clin Dev ; 27: 327-336, 2022 Dec 08.

Article en En | MEDLINE | ID: mdl-36381304

Palabras clave

AAV; CDMS; adeno-associated virus; charge detection mass spectrometry; genome release; mass spectrometry; rAAV; thermal stability

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Methods Clin Dev Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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