Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in <i>Toxoplasma gondii</i>.

Vo, Kim Chi; Ruga, Liberta; Psathaki, Olympia Ekaterini; Franzkoch, Rico; Distler, Ute; Tenzer, Stefan; Hensel, Michael; Hegemann, Peter; Gupta, Nishith

Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii.

Vo, Kim Chi; Ruga, Liberta; Psathaki, Olympia Ekaterini; Franzkoch, Rico; Distler, Ute; Tenzer, Stefan; Hensel, Michael; Hegemann, Peter; Gupta, Nishith.

Afiliación

Vo KC; Department of Molecular Parasitology, Institute of Biology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.
Ruga L; Department of Molecular Parasitology, Institute of Biology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.
Psathaki OE; University of Osnabrück, Center of Cellular Nanoanalytics (CellNanOs), Integrated Bioimaging Faciltiy (iBiOs), Germany.
Franzkoch R; University of Osnabrück, Center of Cellular Nanoanalytics (CellNanOs), Integrated Bioimaging Faciltiy (iBiOs), Germany.
Distler U; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University Mainz, Mainz, Germany.
Tenzer S; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University Mainz, Mainz, Germany.
Hensel M; University of Osnabrück, Center of Cellular Nanoanalytics (CellNanOs), Integrated Bioimaging Faciltiy (iBiOs), Germany.
Hegemann P; Department of Molecular Parasitology, Institute of Biology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.
Gupta N; Department of Molecular Parasitology, Institute of Biology, Faculty of Life Sciences, Humboldt University, Berlin, Germany.

Comput Struct Biotechnol J ; 20: 5775-5789, 2022.

Article en En | MEDLINE | ID: mdl-36382189

Palabras clave

3'IT, 3'-insertional tagging; Apicomplexa; COS, crossover sequence; CRISPR, clustered regularly interspaced short palindromic repeats; DHFR-TS, dihydrofolate reductase thymidylate synthase; HFF, human foreskin fibroblast; HXGPRT, hypoxanthine-xanthine-guanine phosphoribosyl transferase; IMC, inner membrane complex; Lytic cycle; MoI, multiplicity of infection; PDE, phosphodiesterase; PKA, protein kinase A; PKG, protein kinase G; PM, plasma membrane; Phosphodiesterase; S. C., selection cassette; TEM, transmission electron microscopy; Tachyzoite; cAMP & cGMP signaling; sgRNA, single guide RNA; smHA, spaghetti monster-HA

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Año: 2022 Tipo del documento: Article País de afiliación: Alemania

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google