Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS).

Ogbechi, Joy; Huang, Yi-Shu; Clanchy, Felix I L; Pantazi, Eirini; Topping, Louise M; Darlington, L Gail; Williams, Richard O; Stone, Trevor W

Ogbechi, Joy; Huang, Yi-Shu; Clanchy, Felix I L; Pantazi, Eirini; Topping, Louise M; Darlington, L Gail; Williams, Richard O; Stone, Trevor W.

Afiliación

Ogbechi J; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Huang YS; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Clanchy FIL; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Pantazi E; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Topping LM; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Darlington LG; Internal Medicine, Ashtead Hospital, Ashtead, United Kingdom.
Williams RO; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.
Stone TW; The Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculo-skeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom.

Front Immunol ; 13: 1001956, 2022.

Article en En | MEDLINE | ID: mdl-36389710

Asunto(s)

Quinurenina; Pseudomonas; Humanos; Ratones; Animales; Quinurenina/metabolismo; Pseudomonas aeruginosa; Hierro/metabolismo; Citocinas/metabolismo

Palabras clave

Indoleamine 2 3-dioxygenase (IDO); PQS signaling; Th17 cells and Treg cells; arthritis (including rheumatoid arthritis); kynurenine (KYN); quorum sensing (QS); regulatory T (Treg) cells; tolerance

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas / Quinurenina Límite: Animals / Humans Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Suiza

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