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The miniature CRISPR-Cas12m effector binds DNA to block transcription.
Wu, Wen Y; Mohanraju, Prarthana; Liao, Chunyu; Adiego-Pérez, Belén; Creutzburg, Sjoerd C A; Makarova, Kira S; Keessen, Karlijn; Lindeboom, Timon A; Khan, Tahseen S; Prinsen, Stijn; Joosten, Rob; Yan, Winston X; Migur, Anzhela; Laffeber, Charlie; Scott, David A; Lebbink, Joyce H G; Koonin, Eugene V; Beisel, Chase L; van der Oost, John.
Afiliación
  • Wu WY; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands. Electronic address: wen.wu@wur.nl.
  • Mohanraju P; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Liao C; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), 97080 Würzburg, Germany.
  • Adiego-Pérez B; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Creutzburg SCA; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Makarova KS; National Centre for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
  • Keessen K; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Lindeboom TA; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Khan TS; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Prinsen S; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Joosten R; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • Yan WX; Arbor Biotechnologies, Cambridge, MA 02139, USA.
  • Migur A; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), 97080 Würzburg, Germany.
  • Laffeber C; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands.
  • Scott DA; Arbor Biotechnologies, Cambridge, MA 02139, USA.
  • Lebbink JHG; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands; Department of Radiation Oncology, Erasmus University Medical Center, 3000 CA Rotterdam, the Netherlands.
  • Koonin EV; National Centre for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
  • Beisel CL; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), 97080 Würzburg, Germany; Medical Faculty, University of Würzburg, 97080 Würzburg, Germany.
  • van der Oost J; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands. Electronic address: john.vanderoost@wur.nl.
Mol Cell ; 82(23): 4487-4502.e7, 2022 12 01.
Article en En | MEDLINE | ID: mdl-36427491

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Asociadas a CRISPR Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Asociadas a CRISPR Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos