Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer.

Matsushima, Shingo; Ajiro, Masahiko; Iida, Kei; Chamoto, Kenji; Honjo, Tasuku; Hagiwara, Masatoshi

Matsushima, Shingo; Ajiro, Masahiko; Iida, Kei; Chamoto, Kenji; Honjo, Tasuku; Hagiwara, Masatoshi.

Afiliación

Matsushima S; Department of Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Ajiro M; Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Iida K; Pharmacology Research Laboratories, Watarase Research Center, Kyorin Pharmaceutical Co. Ltd, Tochigi 329-0114, Japan.
Chamoto K; Department of Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Honjo T; Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Hagiwara M; Medical Research Support Center, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.

Sci Transl Med ; 14(673): eabn6056, 2022 11 30.

Article en En | MEDLINE | ID: mdl-36449604

Asunto(s)

Neoplasias Colorrectales; Inmunoterapia; Humanos; Mutación; Linfocitos T CD8-positivos; Perfilación de la Expresión Génica; Neoplasias Colorrectales/terapia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Inmunoterapia Límite: Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Japón

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