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Addressing the challenges of polygenic scores in human genetic research.
Novembre, John; Stein, Catherine; Asgari, Samira; Gonzaga-Jauregui, Claudia; Landstrom, Andrew; Lemke, Amy; Li, Jun; Mighton, Chloe; Taylor, Matthew; Tishkoff, Sarah.
Afiliación
  • Novembre J; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Department of Human Genetics, University of Chicago, Chicago, IL, USA; Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA.
  • Stein C; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA. Electronic address: cmj7@case.edu.
  • Asgari S; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gonzaga-Jauregui C; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; International Laboratory for Human Genome Research, Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma
  • Landstrom A; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Department of Pediatrics, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
  • Lemke A; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Norton Children's Research Institute, affiliated with the University of Louisville School of Medicine, Louisville, KY, USA.
  • Li J; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Mighton C; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Genomics Health Services Research Program, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada; Institute of Health Policy, Management
  • Taylor M; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Adult Medical Genetics Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Tishkoff S; Professional Practice and Social Implications Committee Polygenic Scores Guidance Writing Group, American Society of Human Genetics, Rockville MD, USA; Department of Genetics, Center for Global Genomics and Health Equity, University of Pennsylvania, Philadelphia, PA, USA; Department of Biology, Cent
Am J Hum Genet ; 109(12): 2095-2100, 2022 12 01.
Article en En | MEDLINE | ID: mdl-36459976
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Herencia Multifactorial / Estudio de Asociación del Genoma Completo Tipo de estudio: Guideline / Prognostic_studies Aspecto: Ethics Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Herencia Multifactorial / Estudio de Asociación del Genoma Completo Tipo de estudio: Guideline / Prognostic_studies Aspecto: Ethics Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos