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Ovarian and uterine carcinosarcomas are sensitive in vitro and in vivo to elimusertib, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor.
Manavella, Diego D; McNamara, Blair; Harold, Justin; Bellone, Stefania; Hartwich, Tobias Max Philipp; Yang-Hartwich, Yang; Mutlu, Levent; Zipponi, Margherita; Demirkiran, Cem; Verzosa, Miguel Skyler; Altwerger, Gary; Ratner, Elena; Huang, Gloria S; Clark, Mitchell; Andikyan, Vaagn; Azodi, Masoud; Schwartz, Peter E; Dottino, Peter R; Choi, Jungmin; Alexandrov, Ludmil B; Buza, Natalia; Hui, Pei; Santin, Alessandro D.
Afiliación
  • Manavella DD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • McNamara B; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Harold J; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Hartwich TMP; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Yang-Hartwich Y; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Mutlu L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Zipponi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Demirkiran C; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Verzosa MS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Clark M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Andikyan V; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Dottino PR; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA.
  • Choi J; Department of Biomedical Sciences, Korea University College of Medicine, 02841 Seoul, Republic of Korea.
  • Alexandrov LB; Department of Cellular and Molecular Medicine University of California San Diego, La Jolla, USA.
  • Buza N; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Hui P; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, CT 06520, USA. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 169: 98-105, 2023 02.
Article en En | MEDLINE | ID: mdl-36525930
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Uterinas / Ataxia Telangiectasia / Carcinosarcoma / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Uterinas / Ataxia Telangiectasia / Carcinosarcoma / Antineoplásicos Tipo de estudio: Diagnostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos