Fluorescence Screens for Identifying Central Nervous System-Acting Drug-Biosensor Pairs for Subcellular and Supracellular Pharmacokinetics.

Beatty, Zoe G; Muthusamy, Anand K; Unger, Elizabeth K; Dougherty, Dennis A; Tian, Lin; Looger, Loren L; Shivange, Amol V; Bera, Kallol; Lester, Henry A; Nichols, Aaron L

Beatty, Zoe G; Muthusamy, Anand K; Unger, Elizabeth K; Dougherty, Dennis A; Tian, Lin; Looger, Loren L; Shivange, Amol V; Bera, Kallol; Lester, Henry A; Nichols, Aaron L.

Afiliación

Beatty ZG; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA.
Muthusamy AK; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, USA.
Unger EK; Department of Biochemistry and Molecular Medicine and the Center for Neuroscience, University of California at Davis, Davis, USA.
Dougherty DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, USA.
Tian L; Department of Biochemistry and Molecular Medicine and the Center for Neuroscience, University of California at Davis, Davis, USA.
Looger LL; HHMI Janelia Research Campus, Ashburn, USA.
Shivange AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA.
Bera K; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA.
Lester HA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA.
Nichols AL; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA.

Bio Protoc ; 12(22)2022 Nov 20.

Article en En | MEDLINE | ID: mdl-36532688

Palabras clave

Biosensor; CNS-acting drugs; Directed evolution; Fluorescence screening; Pharmacokinetics; iDrugSnFR

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Bio Protoc Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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