Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.

Chen, Jian; Lin, Xian; He, Juan; Liu, Dandan; He, Lianhua; Zhang, Miaomiao; Luan, Huijie; Hu, Yiping; Tao, Cheng; Wang, Qingwen

Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.

Chen, Jian; Lin, Xian; He, Juan; Liu, Dandan; He, Lianhua; Zhang, Miaomiao; Luan, Huijie; Hu, Yiping; Tao, Cheng; Wang, Qingwen.

Afiliación

Chen J; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Lin X; Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen, Guangdong, China.
He J; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Liu D; Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen, Guangdong, China.
He L; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Zhang M; Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen, Guangdong, China.
Luan H; School of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Hu Y; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Tao C; Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen, Guangdong, China.
Wang Q; Department of Rheumatism and Immunology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.

Clin Transl Med ; 12(12): e1148, 2022 12.

Article en En | MEDLINE | ID: mdl-36536495

Asunto(s)

Artritis Reumatoide; Sinoviocitos; Animales; Ratones; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; ARN Mensajero/metabolismo; Sinoviocitos/metabolismo; Proliferación Celular; Artritis Reumatoide/genética; Fibroblastos/metabolismo; Metiltransferasas/metabolismo

Palabras clave

ICAM2; METTL3; artemisitene; fibroblast-like synoviocytes; rheumatoid arthritis

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Sinoviocitos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Clin Transl Med Año: 2022 Tipo del documento: Article País de afiliación: China

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google