Topical Cannabidiol in the Treatment of Digital Ulcers in Patients with Scleroderma: Comparative Analysis and Literature Review.
Adv Skin Wound Care
; 36(1): 18-23, 2023 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-36537770
ABSTRACT
OBJECTIVE:
To explore the effect of topical cannabidiol (CBD) in treating digital ulcers in patients with systemic sclerosis (SSc).METHODS:
In total, 45 patients with SSc who had digital ulcers were consecutively enrolled between January 2019 and December 2019. Of the participants, 25 were treated with CBD during surgical debridement and 20 were treated with standard local therapy. A numeric rating scale for pain and Health Assessment Questionnaire Disability Index were administered at the baseline and at the end of treatment.RESULTS:
Local treatment with CBD was significantly associated with lower pain scores, higher health assessment scores, and an increase in participants' total hours of sleep. Patients in the control group more frequently required additional analgesic therapy.CONCLUSIONS:
Topical CBD may be a valuable tool to treat pain related to digital ulcers in patients with SSc.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Esclerodermia Localizada
/
Esclerodermia Sistémica
/
Úlcera Cutánea
/
Cannabidiol
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Adv Skin Wound Care
Asunto de la revista:
ENFERMAGEM
Año:
2023
Tipo del documento:
Article