Association Between Prognosis of Acute Retinal Necrosis and Retinal Involvement.
Turk J Ophthalmol
; 52(6): 405-411, 2022 12 28.
Article
en En
| MEDLINE
| ID: mdl-36578219
ABSTRACT
Objectives:
The aims of this study were to describe the clinical presentation and treatment modalities of acute retinal necrosis (ARN) and to evaluate complications and clinical outcomes according to the extent of retinal involvement at initial presentation. Materials andMethods:
The medical records of 52 patients diagnosed with ARN were reviewed and 48 were included in the study. Patients were categorized into two groups according to the extent of retinitis at presentation retinal involvement of 1-2 quadrants (Group A) or 3-4 quadrants (Group B).Results:
The mean age of the 14 women and 34 men at presentation was 51.3±13.6 years (range 27-78). There were 40 unilateral and 8 bilateral cases. There were 11 eyes (19.6%) in Group A and 45 eyes (80.4%) in Group B. Eleven patients (22.9%) had a history of herpes simplex virus/varicella-zoster virus infection. One patient in Group A and 11 patients in Group B had received local or systemic corticosteroid therapy without concomitant antiviral treatment before referral. The median follow-up period was 29 months (range 1-209) in Group A and 8.5 months (range 0.75-209) in Group B. Mean visual acuity (VA) at presentation was 0.42±0.55 LogMAR (range 0-2.0) in Group A and 1.28±0.95 LogMAR (range 0-2.9) in Group B (p<0.05). The presence of endothelial keratic precipitates at presentation was significantly different between two groups (p=0.021). Retinal detachment (RD) occurred in 1 eye (9.1%) in Group A and 30 eyes (66.7%) in Group B (p<0.001). Optic disc pallor was seen in 36.4% (4/11) of eyes in Group A and 71.1% (32/45) of eyes in Group B (p=0.033). Other ocular complications were not significantly different between two groups. Mean final visual acuity was 0.29±0.41 LogMAR in Group A and 1.61±0.90 LogMAR in Group B (p<0.05).Conclusion:
The extent of retinal involvement at presentation affects visual outcomes and this shows the importance of early diagnosis and early initiation of antiviral treatment.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones Virales del Ojo
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Síndrome de Necrosis Retiniana Aguda
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Herpes Zóster Oftálmico
/
Herpes Simple
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
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Risk_factors_studies
/
Screening_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Turk J Ophthalmol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Turquía