Novel acetic acid derivatives containing quinazolin-4(3H)-one ring: Synthesis, in vitro, and in silico evaluation of potent aldose reductase inhibitors.

Tokali, Feyzi Sinan; Demir, Yeliz; Türkes, Cüneyt; Dinçer, Büsra; Beydemir, Sükrü

Tokali, Feyzi Sinan; Demir, Yeliz; Türkes, Cüneyt; Dinçer, Büsra; Beydemir, Sükrü.

Afiliación

Tokali FS; Department of Material and Material Processing Technologies, Kars Vocational School, Kafkas University, Kars, Turkey.
Demir Y; Department of Pharmacy Services, Nihat Delibalta Göle Vocational High School, Ardahan University, Ardahan, Turkey.
Türkes C; Department of Biochemistry, Faculty of Pharmacy, Erzincan Binali Yildirim University, Erzincan, Turkey.
Dinçer B; Department of Pharmacology, Faculty of Pharmacy, Erzincan Binali Yildirim University, Erzincan, Turkey.
Beydemir S; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey.

Drug Dev Res ; 84(2): 275-295, 2023 04.

Article en En | MEDLINE | ID: mdl-36598092

Asunto(s)

Ácido Acético; Aldehído Reductasa; Aldehído Reductasa/metabolismo; Inhibidores Enzimáticos/química; Simulación del Acoplamiento Molecular; Relación Estructura-Actividad; Humanos; Femenino

Palabras clave

ADME; aldose reductase; molecular docking; quinazolines; synthesis

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aldehído Reductasa / Ácido Acético Límite: Female / Humans Idioma: En Revista: Drug Dev Res Año: 2023 Tipo del documento: Article País de afiliación: Turquía

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google