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The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease.
Valis, Martin; Dlabkova, Alzbeta; Hort, Jakub; Angelucci, Francesco; Pejchal, Jaroslav; Kuca, Kamil; Pavelek, Zbysek; Karasova, Jana Zdarova; Novotny, Michal.
Afiliación
  • Valis M; Department of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic. Electronic address: martin.valis@fnhk.cz.
  • Dlabkova A; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, the University of Defense in Brno, Hradec Kralove, Czech Republic. Electronic address: alzbeta.dlabkova@unob.cz.
  • Hort J; Department of Neurology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic. Electronic address: jakub.hort@gmail.com.
  • Angelucci F; Department of Neurology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.
  • Pejchal J; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, the University of Defense in Brno, Hradec Kralove, Czech Republic.
  • Kuca K; Department of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic; Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic. Electronic address: kamil.kuca@fnhk.cz.
  • Pavelek Z; Department of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic.
  • Karasova JZ; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, the University of Defense in Brno, Hradec Kralove, Czech Republic; Department of Neurology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.
  • Novotny M; Department of Neurology, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic. Electronic address: m.novas82@gmail.com.
Biomed Pharmacother ; 159: 114223, 2023 Mar.
Article en En | MEDLINE | ID: mdl-36630846
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Donepezilo Tipo de estudio: Clinical_trials Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Enfermedad de Alzheimer / Donepezilo Tipo de estudio: Clinical_trials Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2023 Tipo del documento: Article Pais de publicación: Francia