Assessment of the structures contribution (crystalline and mesophases) and mechanical properties of polycaprolactone/pluronic blends.
J Mech Behav Biomed Mater
; 139: 105668, 2023 03.
Article
en En
| MEDLINE
| ID: mdl-36638636
ABSTRACT
Films of biodegradable blends of polycaprolactone (PCL) and Pluronics F68 and F127 were manufactured by an industrial thermo-mechanical process to be applied as potential delivery systems. The effects of Pluronics on the structure (mesophase organization), and thermal and mechanical properties of polycaprolactone were investigated using differential scanning calorimetry (DSC), small-angle X-ray scattering (SAXS), X-ray diffraction (XRD), polarized optical microscopy (POM) and tensile mechanical tests. The addition of Pluronics affected the crystallization process by changing the relative amounts of crystalline, amorphous, and meso- (condis + plastic) phases. The melting transition and XRD profiles were deconvoluted to assess the individual contribution of the different crystal morphologies. Furthermore, it was found that the mechanical properties of the blends depended on the ratio and type of Pluronic. Thus, Pluronic F127 showed a larger mesophase content than its F68 counterpart with PCL and blends with enhanced ductility.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poliésteres
/
Poloxámero
Idioma:
En
Revista:
J Mech Behav Biomed Mater
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2023
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS