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The Remarkable Outer Hair Cell: Proceedings of a Symposium in Honour of W. E. Brownell.
Ashmore, Jonathan F; Oghalai, John S; Dewey, James B; Olson, Elizabeth S; Strimbu, Clark E; Wang, Yi; Shera, Christopher A; Altoè, Alessandro; Abdala, Carolina; Elgoyhen, Ana B; Eatock, Ruth Anne; Raphael, Robert M.
Afiliación
  • Ashmore JF; UCL Ear Institute, University College London, London, UK.
  • Oghalai JS; Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, USA.
  • Dewey JB; Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, USA.
  • Olson ES; Department of Otolaryngology Head and Neck Surgery, Vagelos College of Physicians and Surgeons, Columbia University, New York City, USA.
  • Strimbu CE; Department of Otolaryngology Head and Neck Surgery, Vagelos College of Physicians and Surgeons, Columbia University, New York City, USA.
  • Wang Y; Department of Otolaryngology Head and Neck Surgery, Vagelos College of Physicians and Surgeons, Columbia University, New York City, USA.
  • Shera CA; Caruso Department of Otolaryngology and Department of Physics and Astronomy, University of Southern California, Los Angeles, USA.
  • Altoè A; Caruso Department of Otolaryngology and Department of Physics and Astronomy, University of Southern California, Los Angeles, USA.
  • Abdala C; Caruso Department of Otolaryngology, University of Southern California, Los Angeles, USA.
  • Elgoyhen AB; Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres" (INGEBI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
  • Eatock RA; Department of Neurobiology, University of Chicago, Chicago, USA.
  • Raphael RM; Department of Bioengineering, Rice University, Houston, USA. rraphael@rice.edu.
J Assoc Res Otolaryngol ; 24(2): 117-127, 2023 04.
Article en En | MEDLINE | ID: mdl-36648734
ABSTRACT
In 1985, Bill Brownell and colleagues published the remarkable observation that cochlear outer hair cells (OHCs) express voltage-driven mechanical motion electromotility. They proposed OHC electromotility as the mechanism for the elusive "cochlear amplifier" required to explain the sensitivity of mammalian hearing. The finding and hypothesis stimulated an explosion of experiments that have transformed our understanding of cochlear mechanics and physiology, the evolution of hair cell structure and function, and audiology. Here, we bring together examples of current research that illustrate the continuing impact of the discovery of OHC electromotility.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cóclea / Células Ciliadas Auditivas Externas Límite: Animals Idioma: En Revista: J Assoc Res Otolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cóclea / Células Ciliadas Auditivas Externas Límite: Animals Idioma: En Revista: J Assoc Res Otolaryngol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido