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Metabolism and pharmacokinetic study of deuterated osimertinib.
Zhan, Xuyi; Bao, Shaoyin; Li, Xumei; Zhou, Shaojun; Dahar, Maha Raja; Lin, Nengming; Chen, Xiugui; Niu, Chengshan; Ji, Kaige; Wu, Yusheng; Zeng, Kui; Tang, Zhihua; Yu, Lushan.
Afiliación
  • Zhan X; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Bao S; Cancer Center, Zhejiang University, Hangzhou, China.
  • Li X; Quzhou Hospital of Traditional Chinese Medicine (Four Provincial Marginal Hospitals of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine), Quzhou, China.
  • Zhou S; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Dahar MR; School of Engineering, Zhejiang University, Hangzhou, China.
  • Lin N; Department of Pharmacy, The Second Hospital of Jiaxing, Jiaxing, China.
  • Chen X; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Niu C; Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Ji K; Cancer Center, Zhejiang University, Hangzhou, China.
  • Wu Y; Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Department of Clinical Pharmacy, Zhejiang University School of Medicine, Hangzhou, China.
  • Zeng K; TYK Medicines, Inc, Hangzhou, China.
  • Tang Z; TYK Medicines, Inc, Hangzhou, China.
  • Yu L; TYK Medicines, Inc, Hangzhou, China.
Biopharm Drug Dispos ; 44(2): 165-174, 2023 Apr.
Article en En | MEDLINE | ID: mdl-36649539
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Biopharm Drug Dispos Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Límite: Animals / Humans Idioma: En Revista: Biopharm Drug Dispos Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido