Whole genome sequencing of <i>CCR5</i> CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits.

Schmidt, Jenna Kropp; Kim, Yun Hee; Strelchenko, Nick; Gierczic, Sarah R; Pavelec, Derek; Golos, Thaddeus G; Slukvin, Igor I

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits.

Schmidt, Jenna Kropp; Kim, Yun Hee; Strelchenko, Nick; Gierczic, Sarah R; Pavelec, Derek; Golos, Thaddeus G; Slukvin, Igor I.

Afiliación

Schmidt JK; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Kim YH; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Strelchenko N; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Gierczic SR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Pavelec D; University of Wisconsin Biotechnology Center, University of Wisconsin-Madison, Madison, WI, United States.
Golos TG; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Slukvin II; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, United States.

Front Genome Ed ; 4: 1031275, 2022.

Article en En | MEDLINE | ID: mdl-36714391

Palabras clave

CCR5; CRISPR- Cas9; embryo; macaque; whole genome sequencing (WGS)

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Genome Ed Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google