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The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.
Bachtler, Nadine; Torres, Sandra; Ortiz, Cristina; Schierwagen, Robert; Tyc, Olaf; Hieber, Christoph; Berres, Marie-Luise; Meier, Caroline; Kraus, Nico; Zeuzem, Stefan; Nijmeijer, Bart; Pronk, Sebas; Trebicka, Jonel; Klein, Sabine.
Afiliación
  • Bachtler N; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Torres S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Ortiz C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Schierwagen R; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Tyc O; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Hieber C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Berres ML; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
  • Meier C; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Kraus N; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Zeuzem S; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Nijmeijer B; LinXis BV, Amsterdam, The Netherlands.
  • Pronk S; LinXis BV, Amsterdam, The Netherlands.
  • Trebicka J; Department of Internal Medicine I, Goethe University Frankfurt, Frankfurt, Germany.
  • Klein S; European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain.
PLoS One ; 18(1): e0270288, 2023.
Article en En | MEDLINE | ID: mdl-36719899
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Quinasas Asociadas a rho Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Quinasas Asociadas a rho Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos