Atorvastatin downregulates plasma procarboxypeptidase U concentrations and improves fibrinolytic potential dose-dependently in hyperlipidemic individuals.

Claesen, Karen; Sim, Yani; Basir, Shahir; De Belder, Simon; van den Keybus, Tinne; Van Edom, Glenn; Stoffelen, Hilde; De Keulenaer, Gilles W; Bosmans, Johan; Bringmans, Tijs; De Meester, Ingrid; Hendriks, Dirk

Claesen, Karen; Sim, Yani; Basir, Shahir; De Belder, Simon; van den Keybus, Tinne; Van Edom, Glenn; Stoffelen, Hilde; De Keulenaer, Gilles W; Bosmans, Johan; Bringmans, Tijs; De Meester, Ingrid; Hendriks, Dirk.

Afiliación

Claesen K; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Sim Y; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Basir S; Faculty of Medicine and Health, University of Antwerp, Antwerp, Belgium.
De Belder S; General practitioners' group Epione, Edegem, Belgium.
van den Keybus T; General practitioners' group Epione, Edegem, Belgium.
Van Edom G; General practitioners' group Epione, Edegem, Belgium.
Stoffelen H; General practitioners' group Epione, Edegem, Belgium.
De Keulenaer GW; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium; Department of Cardiology ZNA Hospital, Antwerp, Belgium.
Bosmans J; Department of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Bringmans T; Department of Cardiology, Antwerp University Hospital, Edegem, Belgium.
De Meester I; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.
Hendriks D; Laboratory of Medical Biochemistry, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium. Electronic address: dirk.hendriks@uantwerpen.be.

J Thromb Haemost ; 21(5): 1266-1273, 2023 05.

Article en En | MEDLINE | ID: mdl-36740042

Asunto(s)

Carboxipeptidasa B2; Inhibidores de Hidroximetilglutaril-CoA Reductasas; Humanos; Atorvastatina/farmacología; Atorvastatina/uso terapéutico; Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico; Proyectos Piloto; Terapia Trombolítica

Palabras clave

Atorvastatin; HMG-CoA reductase inhibitors; carboxypeptidase B2; carboxypeptidase U; hypercholesterolemia; thrombin-activatable fibrinolysis inhibitor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Carboxipeptidasa B2 Límite: Humans Idioma: En Revista: J Thromb Haemost Asunto de la revista: HEMATOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Bélgica

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