A Ubiquitous Chromatin Opening Element and DNA Demethylation Facilitate Doxycycline-Controlled Expression during Differentiation and in Transgenic Mice.

Gödecke, Natascha; Herrmann, Sabrina; Weichelt, Viola; Wirth, Dagmar

Gödecke, Natascha; Herrmann, Sabrina; Weichelt, Viola; Wirth, Dagmar.

Afiliación

Gödecke N; RG Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Herrmann S; RG Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Weichelt V; RG Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Wirth D; RG Model Systems for Infection and Immunity, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.

ACS Synth Biol ; 12(2): 482-491, 2023 02 17.

Article en En | MEDLINE | ID: mdl-36755406

Asunto(s)

Cromatina; Doxiciclina; Ratones; Animales; Ratones Transgénicos; Doxiciclina/farmacología; Desmetilación del ADN; Transgenes/genética; Diferenciación Celular/genética

Palabras clave

Tet-on system; UCOE; expression silencing during differentiation; inducible gene expression; transgenic mice

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Doxiciclina Límite: Animals Idioma: En Revista: ACS Synth Biol Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos

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