Rare genetic variants underlie outlying levels of DNA methylation and gene-expression.

Chundru, V Kartik; Marioni, Riccardo E; Prendergast, James G D; Lin, Tian; Beveridge, Allan J; Martin, Nicholas G; Montgomery, Grant W; Hume, David A; Deary, Ian J; Visscher, Peter M; Wray, Naomi R; McRae, Allan F

Chundru, V Kartik; Marioni, Riccardo E; Prendergast, James G D; Lin, Tian; Beveridge, Allan J; Martin, Nicholas G; Montgomery, Grant W; Hume, David A; Deary, Ian J; Visscher, Peter M; Wray, Naomi R; McRae, Allan F.

Afiliación

Chundru VK; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Marioni RE; Wellcome Sanger Institute, Hinxton CB10 1RQ, UK.
Prendergast JGD; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh EH4 2XU, UK.
Lin T; The Roslin Institute, The University of Edinburgh, Midlothian EH25 9RG, UK.
Beveridge AJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Martin NG; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, The University of Glasgow, Glasgow G61 1QH, UK.
Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.
Hume DA; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Deary IJ; Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.
Visscher PM; Lothian Birth Cohorts, Department of Psychology, The University of Edinburgh, Edinburgh EH8 9JZ, UK.
Wray NR; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
McRae AF; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Hum Mol Genet ; 32(11): 1912-1921, 2023 05 18.

Article en En | MEDLINE | ID: mdl-36790133

Asunto(s)

Metilación de ADN; Regulación de la Expresión Génica; Humanos; Metilación de ADN/genética; Fenotipo; Herencia Multifactorial; Epigénesis Genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Expresión Génica / Metilación de ADN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2023 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

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