Metabolism of periodontal pathobionts: Their regulatory roles in the dysbiotic microbiota.
Mol Oral Microbiol
; 38(3): 181-188, 2023 06.
Article
en En
| MEDLINE
| ID: mdl-36811357
ABSTRACT
The onset and development of periodontitis centers around microbiota dysbiosis and disrupted host responses. Dynamic metabolic activities of the subgingival microbiota modify the polymicrobial community, shape the microenvironment, and modulate the host response. A complicated metabolic network exists in interspecies interactions between periodontal pathobionts and commensals, which can lead to the development of dysbiotic plaque. Dysbiotic subgingival microbiota undergo metabolic interactions with the host and disrupt host-microbe equilibrium. In this review, we discuss the metabolic profiles of the subgingival microbiota, the metabolic crosstalk in polymicrobial communities, including pathobionts and commensals, and the metabolic interactions between microbes and the host.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Placa Dental
/
Microbiota
Límite:
Humans
Idioma:
En
Revista:
Mol Oral Microbiol
Año:
2023
Tipo del documento:
Article
País de afiliación:
China