Optimization of recombinant antibody production based on the vector design and the level of metabolites for generation of Ig- producing stable cell lines.

Toporova, V A; Argentova, V V; Aliev, T K; Panina, A A; Dolgikh, D A; Kirpichnikov, M P

Toporova, V A; Argentova, V V; Aliev, T K; Panina, A A; Dolgikh, D A; Kirpichnikov, M P.

Afiliación

Toporova VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya ul. 16/10, GSP-7, Moscow, 117997, Russia.
Argentova VV; Department of Bioengineering, Biology Faculty, Lomonosov Moscow State University, Leninskiye gory 1-12, Moscow, 119234, Russia. vivargmsu@yandex.ru.
Aliev TK; Department of Chemical Enzymology, School of Chemistry, Lomonosov Moscow State University, Leninskiye gory 1-3, Moscow, 119234, Russia.
Panina AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya ul. 16/10, GSP-7, Moscow, 117997, Russia.
Dolgikh DA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya ul. 16/10, GSP-7, Moscow, 117997, Russia.
Kirpichnikov MP; Department of Bioengineering, Biology Faculty, Lomonosov Moscow State University, Leninskiye gory 1-12, Moscow, 119234, Russia.

J Genet Eng Biotechnol ; 21(1): 23, 2023 Feb 22.

Article en En | MEDLINE | ID: mdl-36811683

Palabras clave

Bipromoter/bicistronic plasmid; Expression vector; Level metabolites; Stable cell lines; mAbs production

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Genet Eng Biotechnol Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Países Bajos

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