Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification.

Al-Akashi, Ziadoon; Zujur, Denise; Kamiya, Daisuke; Kato, Tomohisa; Kondo, Toru; Ikeya, Makoto

Al-Akashi, Ziadoon; Zujur, Denise; Kamiya, Daisuke; Kato, Tomohisa; Kondo, Toru; Ikeya, Makoto.

Afiliación

Al-Akashi Z; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Zujur D; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Kamiya D; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
Kato T; Takeda-CiRA Joint Program, Fujisawa, Kanagawa, Japan.
Kondo T; Medical Research Institute, Kanazawa Medical University, Kanazawa, Japan.
Ikeya M; Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.

Front Cell Dev Biol ; 11: 1089945, 2023.

Article en En | MEDLINE | ID: mdl-36814599

Palabras clave

brequinar (BRQ); dihydroorotate dehydrogenase (DHODH); induced mesenchymal stromal cells (iMSCs); induced pluripotent stem cells (hiPSC); mesenchymal stem/stromal cells (MSCs); pyrimidine biosynthesis; survival

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Cell Dev Biol Año: 2023 Tipo del documento: Article País de afiliación: Japón

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