Associations of Anaplasma phagocytophilum Bacteria Variants in Ixodes scapularis Ticks and Humans, New York, USA.
Emerg Infect Dis
; 29(3)2023 03.
Article
en En
| MEDLINE
| ID: mdl-36823761
ABSTRACT
Anaplasmosis, caused by the tickborne bacterium Anaplasma phagocytophilum, is an emerging public health threat in the United States. In the northeastern United States, the blacklegged tick (Ixodes scapularis) transmits the human pathogenic genetic variant of A. phagocytophilum (Ap-ha) and a nonpathogenic variant (Ap-V1). New York has recently experienced a rapid and geographically focused increase in cases of anaplasmosis. We analyzed A. phagocytophilum-infected I. scapularis ticks collected across New York during 2008-2020 to differentiate between variants and calculate an entomological risk index (ERI) for each. Ap-ha ERI varied between regions and increased in all regions during the final years of the study. Space-time scan analyses detected expanding clusters of Ap-ha located within documented anaplasmosis hotspots. Ap-ha ERI was more positively correlated with anaplasmosis incidence than non-genotyped A. phagocytophilum ERI. Our findings help elucidate the relationship between the spatial ecology of A. phagocytophilum variants and anaplasmosis.
Palabras clave
Anaplasma phagocytophilum; Ixodes; New York; O'Connor C; Rose L; Russell A; Sommer J; Suggested citation for this article: Prusinski M; USA. Emerg Infect Dis. 2023 Mar [date cited]. https://doi.org/10.3201/eid2903.220320; United States; White J; anaplasmosis; bacteria; et al. Associations of Anaplasma phagocytophilum bacteria variants in Ixodes scapularis ticks and humans; genetic variants; geographic information systems; population genetics; public health surveillance; space-time clustering; spatiotemporal analysis; ticks; vector-borne infections; zoonoses
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ixodes
/
Anaplasma phagocytophilum
/
Anaplasmosis
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
/
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Emerg Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2023
Tipo del documento:
Article