Oligodendrocytes Prune Axons Containing &#945;-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?

De Nuccio, Francesco; Kashyrina, Marianna; Serinelli, Francesca; Laferrière, Florent; Lofrumento, Dario Domenico; De Giorgi, Francesca; Ichas, François

Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?

De Nuccio, Francesco; Kashyrina, Marianna; Serinelli, Francesca; Laferrière, Florent; Lofrumento, Dario Domenico; De Giorgi, Francesca; Ichas, François.

Afiliación

De Nuccio F; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Kashyrina M; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Serinelli F; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Laferrière F; Institut des Maladies Neurodégénératives, CNRS, Université de Bordeaux, UMR 5293, 33076 Bordeaux, France.
Lofrumento DD; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
De Giorgi F; Institut des Maladies Neurodégénératives, CNRS, Université de Bordeaux, UMR 5293, 33076 Bordeaux, France.
Ichas F; Institut des Maladies Neurodégénératives, CNRS, Université de Bordeaux, UMR 5293, 33076 Bordeaux, France.

Biomolecules ; 13(2)2023 02 01.

Article en En | MEDLINE | ID: mdl-36830639

Asunto(s)

Atrofia de Múltiples Sistemas; Sinucleinopatías; Humanos; Ratones; Animales; alfa-Sinucleína/metabolismo; Atrofia de Múltiples Sistemas/patología; Cuerpos de Lewy/metabolismo; Cuerpos de Inclusión/metabolismo; Sinucleinopatías/metabolismo; Oligodendroglía/metabolismo; Neuritas/metabolismo; Ratones Transgénicos; Encéfalo/metabolismo

Palabras clave

Lewy neurite; PFFs; anterior commissure; axonal pruning; glial cytoplasmic inclusion; multiple system atrophy; oligodendrocyte; seeding; spread; α-Synuclein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Atrofia de Múltiples Sistemas / Sinucleinopatías Límite: Animals / Humans Idioma: En Revista: Biomolecules Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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