Remodeling oncogenic transcriptomes by small molecules targeting NONO.

Kathman, Stefan G; Koo, Seong Joo; Lindsey, Garrett L; Her, Hsuan-Lin; Blue, Steven M; Li, Haoxin; Jaensch, Steffen; Remsberg, Jarrett R; Ahn, Kay; Yeo, Gene W; Ghosh, Brahma; Cravatt, Benjamin F

Kathman, Stefan G; Koo, Seong Joo; Lindsey, Garrett L; Her, Hsuan-Lin; Blue, Steven M; Li, Haoxin; Jaensch, Steffen; Remsberg, Jarrett R; Ahn, Kay; Yeo, Gene W; Ghosh, Brahma; Cravatt, Benjamin F.

Afiliación

Kathman SG; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. skathman@scripps.edu.
Koo SJ; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Beerse, Belgium.
Lindsey GL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Her HL; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA.
Blue SM; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
Li H; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Jaensch S; High Dimensional and Computational Biology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Beerse, Belgium.
Remsberg JR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Ahn K; Molecular and Cellular Pharmacology, Discovery Technologies and Molecular Pharmacology, Janssen Research and Development, Spring House, PA, USA. kayahn2@gmail.com.
Yeo GW; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.
Ghosh B; Discovery Chemistry, Janssen Research and Development, Spring House, PA, USA. bghosh7@its.jnj.com.
Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. cravatt@scripps.edu.

Nat Chem Biol ; 19(7): 825-836, 2023 07.

Article en En | MEDLINE | ID: mdl-36864190

Asunto(s)

Proteínas de Unión al ADN; Transcriptoma; Masculino; Humanos; Proteínas de Unión al ADN/metabolismo; Proteínas de Unión al ARN/química; ARN

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Unión al ADN / Transcriptoma Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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