Cadmium-promoted thyroid hormones disruption mediates ROS, inflammation, Aß and Tau proteins production, gliosis, spongiosis and neurodegeneration in rat basal forebrain.

Sola, Emma; Moyano, Paula; Flores, Andrea; García, José Manuel; García, Jimena; Anadon, María José; Frejo, María Teresa; Pelayo, Adela; de la Cabeza Fernandez, Maria; Del Pino, Javier

Sola, Emma; Moyano, Paula; Flores, Andrea; García, José Manuel; García, Jimena; Anadon, María José; Frejo, María Teresa; Pelayo, Adela; de la Cabeza Fernandez, Maria; Del Pino, Javier.

Afiliación

Sola E; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
Moyano P; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain. Electronic address: pmoyanocires@ucm.es.
Flores A; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
García JM; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
García J; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
Anadon MJ; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28041, Madrid, Spain.
Frejo MT; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain.
Pelayo A; Department of Legal Medicine, Psychiatry and Pathology, Medicine School, Complutense University of Madrid, 28041, Madrid, Spain.
de la Cabeza Fernandez M; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Complutense University of Madrid, 28041, Madrid, Spain.
Del Pino J; Department of Pharmacology and Toxicology, Veterinary School, Complutense University of Madrid, 28040, Madrid, Spain. Electronic address: jdelpino@pdi.ucm.es.

Chem Biol Interact ; 375: 110428, 2023 Apr 25.

Article en En | MEDLINE | ID: mdl-36868496

Asunto(s)

Prosencéfalo Basal; Cadmio; Animales; Masculino; Ratas; Secretasas de la Proteína Precursora del Amiloide/metabolismo; Ácido Aspártico Endopeptidasas/metabolismo; Prosencéfalo Basal/metabolismo; Cadmio/toxicidad; Gliosis/inducido químicamente; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Inflamación; Ratas Wistar; Especies Reactivas de Oxígeno; Proteínas tau/metabolismo; Hormonas Tiroideas

Palabras clave

Aß and Tau proteins; Basal forebrain cholinergic neurons; Cadmium; Inflammatory cytokines; Oxidative stress; T3

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cadmio / Prosencéfalo Basal Límite: Animals Idioma: En Revista: Chem Biol Interact Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Irlanda

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google