Your browser doesn't support javascript.
loading
In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors.
Bourdely, Pierre; Savoldelli, Roberto; Vetillard, Mathias; Anselmi, Giorgio; Helft, Julie; Guermonprez, Pierre.
Afiliación
  • Bourdely P; Institut Cochin, INSERM U1016, CNRS UMR8104, Université de Paris Cité, Paris, France. pierre.bourdely@inserm.fr.
  • Savoldelli R; King's College London, Centre for Inflammation Biology and Cancer Immunology, London, UK.
  • Vetillard M; Université de Paris, INSERM U1149, CNRS erl8252, Centre for Inflammation Research, Université de Paris Cité, Paris, France.
  • Anselmi G; Université de Paris, INSERM U1149, CNRS erl8252, Centre for Inflammation Research, Université de Paris Cité, Paris, France.
  • Helft J; King's College London, Centre for Inflammation Biology and Cancer Immunology, London, UK.
  • Guermonprez P; Oxford University, Radcliffe Department of Medicine, Oxford, UK.
Methods Mol Biol ; 2618: 121-132, 2023.
Article en En | MEDLINE | ID: mdl-36905513
ABSTRACT
Dendritic cells (DCs) are professional antigen-presenting cells controlling the activation of T cells and thus regulating adaptive immune response against pathogens or tumors. Modeling human DC differentiation and function is crucial for our understanding of immune response and the development of new therapies. Considering DC rarity in human blood, in vitro systems allowing their faithful generation are needed. This chapter will describe a DC differentiation method based on the co-culture of CD34+ cord blood progenitors together with mesenchymal stromal cells (eMSCs) engineered to deliver growth factors and chemokines.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Dendríticas / Sangre Fetal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Francia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Dendríticas / Sangre Fetal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Francia