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Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction.
Chen, Jia-Yun; Hug, Clemens; Reyes, José; Tian, Chengzhe; Gerosa, Luca; Fröhlich, Fabian; Ponsioen, Bas; Snippert, Hugo J G; Spencer, Sabrina L; Jambhekar, Ashwini; Sorger, Peter K; Lahav, Galit.
Afiliación
  • Chen JY; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Hug C; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Reyes J; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Tian C; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303, USA; Research Center for Molecular Medicine, Austrian Academy of Sciences, Vienna, Austria.
  • Gerosa L; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Genentech, Inc, South San Francisco, CA 94080, USA.
  • Fröhlich F; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Ponsioen B; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands.
  • Snippert HJG; Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands.
  • Spencer SL; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303, USA; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303, USA.
  • Jambhekar A; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Ludwig Center at Harvard Medical School, Boston, MA, USA.
  • Sorger PK; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Ludwig Center at Harvard Medical School, Boston, MA, USA. Electronic address: peter_sorger@hms.harvard.edu.
  • Lahav G; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA; Ludwig Center at Harvard Medical School, Boston, MA, USA. Electronic address: galit@hms.harvard.edu.
Cell Rep ; 42(3): 112252, 2023 03 28.
Article en En | MEDLINE | ID: mdl-36920903
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Proteínas Proto-Oncogénicas B-raf Límite: Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Proteínas Proto-Oncogénicas B-raf Límite: Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos