Prominent dermal accumulation of Russell bodies underlying pseudocarcinomatous hyperplasia with fungal infection.
Nagoya J Med Sci
; 85(1): 123-126, 2023 Feb.
Article
en En
| MEDLINE
| ID: mdl-36923611
ABSTRACT
Blockade of the secretion of immunoglobulins leads to their accumulation in plasma cells, resulting in condensed immunoglobulins in the rough endoplasmic reticulum of plasma cells, termed Russell bodies. They are sometimes found in lymphoplasmacellular inflammation of the intestinal mucosa and in lymphoid cell malignancies, but only very rarely in skin diseases. Here, we report an 86-year-old female who presented with a lesion with the prominent accumulation of Russell bodies underlying pseudocarcinomatous hyperplasia with fungal infection in the face. Immunohistochemical staining showed the cells containing Russell bodies to be positive for CD138 and the Russell bodies to be positive for immunoglobulin κ and λ light chains. The present case suggests that when inflammatory cell infiltration with abundant round intracellular eosinophilic materials is observed in the dermis, the dermal accumulation of Russell bodies should be considered in cases with reactive pseudocarcinomatous hyperplasia with fungal infection.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Piel
/
Micosis
Límite:
Aged80
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Female
/
Humans
Idioma:
En
Revista:
Nagoya J Med Sci
Año:
2023
Tipo del documento:
Article
País de afiliación:
Japón