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Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion.
Lamarche, Caroline; Ward-Hartstonge, Kirsten; Mi, Tian; Lin, David T S; Huang, Qing; Brown, Andrew; Edwards, Karlie; Novakovsky, Gherman E; Qi, Christopher N; Kobor, Michael S; Zebley, Caitlin C; Weber, Evan W; Mackall, Crystal L; Levings, Megan K.
Afiliación
  • Lamarche C; Department of Surgery, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Ward-Hartstonge K; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
  • Mi T; Department of Medicine, Hôpital Maisonneuve-Rosemont Research Center, Université de Montréal, Montreal H1T 2M4, QC, Canada.
  • Lin DTS; Department of Surgery, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Huang Q; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
  • Brown A; Department of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.
  • Edwards K; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
  • Novakovsky GE; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
  • Qi CN; Department of Medical Genetics, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Kobor MS; Department of Surgery, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Zebley CC; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
  • Weber EW; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
  • Mackall CL; School of Biomedical Engineering, University of British Columbia, Vancouver V6T 1Z4, BC, Canada.
  • Levings MK; BC Children's Hospital Research Institute, Vancouver V5Z 4H4, BC, Canada.
Proc Natl Acad Sci U S A ; 120(14): e2219086120, 2023 04 04.
Article en En | MEDLINE | ID: mdl-36972454
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Quiméricos de Antígenos / Enfermedad Injerto contra Huésped Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Quiméricos de Antígenos / Enfermedad Injerto contra Huésped Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos