A CAD System for Lung Cancer Detection Using Hybrid Deep Learning Techniques.

ABSTRACT

Lung cancer starts and spreads in the tissues of the lungs, more specifically, in the tissue that forms air passages. This cancer is reported as the leading cause of cancer deaths worldwide. In addition to being the most fatal, it is the most common type of cancer. Nearly 47,000 patients are diagnosed with it annually worldwide. This article proposes a fully automated and practical system to identify and classify lung cancer. This system aims to detect cancer in its early stage to save lives if possible or reduce the death rates. It involves a deep convolutional neural network (DCNN) technique, VGG-19, and another deep learning technique, long short-term memory networks (LSTMs). Both tools detect and classify lung cancers after being customized and integrated. Furthermore, image segmentation techniques are applied. This system is a type of computer-aided diagnosis (CAD). After several experiments on MATLAB were conducted, the results show that this system achieves more than 98.8% accuracy when using both tools together. Various schemes were developed to evaluate the considered disease. Three lung cancer datasets, downloaded from the Kaggle website and the LUNA16 grad challenge, were used to train the algorithm, test it, and prove its correctness. Lastly, a comparative evaluation between the proposed approach and some works from the literature is presented. This evaluation focuses on the four performance metrics accuracy, recall, precision, and F-score. This system achieved an average of 99.42% accuracy and 99.76, 99.88, and 99.82% for recall, precision, and F-score, respectively, when VGG-19 was combined with LSTMs. In addition, the results of the comparison evaluation show that the proposed algorithm outperforms other methods and produces exquisite findings. This study concludes that this model can be deployed to aid and support physicians in diagnosing lung cancer correctly and accurately. This research reveals that the presented method has functionality, competence, and value among other implemented models.