A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics.
Sci Adv
; 9(13): eadf9717, 2023 03 29.
Article
en En
| MEDLINE
| ID: mdl-36989362
ABSTRACT
We introduce a cost-effective, robust high-throughput-compatible plasma depletion method enabling in-depth profiling of plasma that detects >1300 proteins per run with a throughput of 60 samples per day. The method has been fully validated by processing >3000 samples with no apparent batch effect at a cost for the depletion step of ~$2.5 per sample.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas
/
Proteómica
Tipo de estudio:
Health_economic_evaluation
Idioma:
En
Revista:
Sci Adv
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos