Diagnostic problems in multiple sclerosis. Two cases with clinical diagnosis of MS showing only a diffusely growing malignant astrocytoma.
Eur Neurol
; 25(3): 197-207, 1986.
Article
en En
| MEDLINE
| ID: mdl-3699070
ABSTRACT
Two cases are presented with a long clinical history of multiple sclerosis (MS) before the diagnosis of an intracranial brain tumor. In the subsequent brain autopsy, however, both cases presented a diffusely growing anaplastic astrocytoma, only, and no changes similar to MS were seen. Diffuse tumor growth was noted in periventricular brain tissue and extended down to pons or medulla. Immunohistochemically, a positive staining for glial fibrillar acidic protein was observed in both cases and in the second case, which presented an increased amount of cerebrospinal fluid IgG, also a positive staining for immunoglobulins was seen. These case histories and subsequent neuropathological findings are presented as examples of diagnostic difficulties in MS, especially in cases with diffusely growing gliomas.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Astrocitoma
/
Neoplasias del Ventrículo Cerebral
/
Esclerosis Múltiple
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur Neurol
Año:
1986
Tipo del documento:
Article