<i>Fusobacterium nucleatum</i> promotes esophageal squamous cell carcinoma progression and chemoresistance by enhancing the secretion of chemotherapy-induced senescence-associated secretory phenotype via activation of DNA damage response pathway.

Zhang, Jian-Wei; Zhang, Dan; Yin, Hai-Sen; Zhang, Han; Hong, Kun-Qiao; Yuan, Jing-Ping; Yu, Bao-Ping

Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression and chemoresistance by enhancing the secretion of chemotherapy-induced senescence-associated secretory phenotype via activation of DNA damage response pathway.

Zhang, Jian-Wei; Zhang, Dan; Yin, Hai-Sen; Zhang, Han; Hong, Kun-Qiao; Yuan, Jing-Ping; Yu, Bao-Ping.

Afiliación

Zhang JW; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Zhang D; Key Laboratory of Hubei Province for Digestive System Diseases, Wuhan, Hubei, PR China.
Yin HS; Department of Gastroenterology, Chongqing University Cancer Hospital, Chongqing, PR China.
Zhang H; Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, PR China.
Hong KQ; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Yuan JP; Key Laboratory of Hubei Province for Digestive System Diseases, Wuhan, Hubei, PR China.
Yu BP; Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.

Gut Microbes ; 15(1): 2197836, 2023.

Article en En | MEDLINE | ID: mdl-37017266

Asunto(s)

Antineoplásicos; Neoplasias Esofágicas; Carcinoma de Células Escamosas de Esófago; Microbioma Gastrointestinal; Humanos; Carcinoma de Células Escamosas de Esófago/tratamiento farmacológico; Carcinoma de Células Escamosas de Esófago/genética; Fusobacterium nucleatum; Fenotipo Secretor Asociado a la Senescencia; Neoplasias Esofágicas/tratamiento farmacológico; Neoplasias Esofágicas/genética; Resistencia a Antineoplásicos/genética; Medios de Cultivo Condicionados/farmacología; Hibridación Fluorescente in Situ; ARN Ribosómico 16S; Senescencia Celular; Recurrencia Local de Neoplasia; Antineoplásicos/farmacología; Daño del ADN

Palabras clave

Fusobacterium nucleatum; cellular senescence; chemoresistance; esophageal squamous cell carcinoma; senescence-associated secretory phenotype

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Microbioma Gastrointestinal / Carcinoma de Células Escamosas de Esófago / Antineoplásicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Gut Microbes Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

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