HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development.

Tsang, Tiffany; Huerta, Fidel; Liu, Yingpeng; Che, Jianwei; Metivier, Rebecca J; Ferrao, Silas; Donovan, Katherine A; Jones, Lyn H; Zerfas, Breanna L; Nowak, Radoslaw P

Tsang, Tiffany; Huerta, Fidel; Liu, Yingpeng; Che, Jianwei; Metivier, Rebecca J; Ferrao, Silas; Donovan, Katherine A; Jones, Lyn H; Zerfas, Breanna L; Nowak, Radoslaw P.

Afiliación

Tsang T; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Huerta F; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Liu Y; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Che J; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston Massachusetts 02115, United States.
Metivier RJ; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Ferrao S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston Massachusetts 02115, United States.
Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Jones LH; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston Massachusetts 02115, United States.
Zerfas BL; Center for Protein Degradation, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.
Nowak RP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston Massachusetts 02215, United States.

ACS Chem Biol ; 18(4): 933-941, 2023 04 21.

Article en En | MEDLINE | ID: mdl-37018062

Asunto(s)

Cromatografía de Afinidad; Sondas Moleculares; Péptidos; Proteolisis; Endorribonucleasas; Proteínas Nucleares; Péptidos/química; Proteínas Serina-Treonina Quinasas; Factores de Transcripción; Sondas Moleculares/química; Sondas Moleculares/metabolismo; Quimera Dirigida a la Proteólisis/química; Quimera Dirigida a la Proteólisis/metabolismo; Cromatografía de Afinidad/métodos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Sondas Moleculares / Cromatografía de Afinidad / Proteolisis Idioma: En Revista: ACS Chem Biol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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