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Replicative stress in gastroesophageal adenocarcinoma is associated with chromosomal instability and sensitivity to DNA damage response inhibitors.
Sahgal, Pranshu; Patil, Deepa T; Sztupinszki, Zsofia M; Tisza, Viktoria; Spisak, Sandor; Huffman, Brandon; Prosz, Aurel; Singh, Harshabad; Lazaro, Jean-Bernard; Szallasi, Zoltan; Cleary, James M; Sethi, Nilay S.
Afiliación
  • Sahgal P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Patil DT; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
  • Sztupinszki ZM; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA, 02142, USA.
  • Tisza V; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Spisak S; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
  • Huffman B; Danish Cancer Society Research Center, Copenhagen, 2100, Denmark.
  • Prosz A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Singh H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Lazaro JB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Szallasi Z; Danish Cancer Society Research Center, Copenhagen, 2100, Denmark.
  • Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Sethi NS; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
bioRxiv ; 2023 Mar 28.
Article en En | MEDLINE | ID: mdl-37034740

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos