Reducing Cardiac Steatosis: Interventions to Improve Diastolic Function: A Narrative Review.
Curr Probl Cardiol
; 48(8): 101739, 2023 Aug.
Article
en En
| MEDLINE
| ID: mdl-37040852
ABSTRACT
Heart failure is one of the main causes of morbidity and mortality around the globe. Heart failure with preserved ejection fraction is primarily caused by diastolic dysfunction. Adipose tissue deposition in the heart has been previously explained in the pathogenesis of diastolic dysfunction. In this article, we aim to discuss the potential interventions that can reduce the risk of diastolic dysfunction by reducing cardiac adipose tissue. A healthy diet with reduced dietary fat content can reduce visceral adiposity and improve diastolic function. Aerobic and resistance exercises also reduce visceral and epicardial fat and ameliorate diastolic dysfunction. Some medications, include metformin, glucagon-like peptide-1 analogues, dipeptidyl peptidase-4 inhibitors, thiazolidinediones, sodium-glucose co-transporter-2, inhibitors, statins, ACE-Is, and ARBs, have shown different degrees of effectiveness in improving cardiac steatosis and diastolic function. Bariatric surgery has also shown promising results in this field.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inhibidores de la Dipeptidil-Peptidasa IV
/
Insuficiencia Cardíaca
Límite:
Humans
Idioma:
En
Revista:
Curr Probl Cardiol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Irán