Your browser doesn't support javascript.
loading
Assessing the preventive effect of immediate lymphatic reconstruction on the upper extremity lymphedema.
Chung, Jae-Ho; Kwon, Sang-Ho; Jung, Seung-Pil; Park, Seung-Ha; Yoon, Eul-Sik.
Afiliación
  • Chung JH; Department of Plastic and Reconstructive Surgery, Korea University Hospital, Seoul, Republic of Korea.
  • Kwon SH; Institute of Nano, Regeneration, Reconstruction, College of Medicine, Korea University, Seoul, Republic of Korea.
  • Jung SP; Department of Plastic and Reconstructive Surgery, Korea University Hospital, Seoul, Republic of Korea.
  • Park SH; Division of Breast and Endocrine Surgery, Korea University Hospital, Seoul, Republic of Korea.
  • Yoon ES; Department of Plastic and Reconstructive Surgery, Korea University Hospital, Seoul, Republic of Korea.
Gland Surg ; 12(3): 334-343, 2023 Mar 31.
Article en En | MEDLINE | ID: mdl-37057043
ABSTRACT

Background:

An immediate lymphatic reconstruction (ILR) combining axillary reverse lymphatic mapping (ARLM) and lymphovenous anastomosis (LVA) has been gradually in the spotlight as a novel surgical technique to prevent lymphedema. In this study, we investigate the preventive effect of ILR for the risk of upper extremity lymphedema. We will compare the incidence of postoperative lymphedema between the ILR treatment group and the no-try or failure group during the same period with analysis of the effects of different variables.

Methods:

In this retrospective cohort study, we analyzed 213 patients who had undergone mastectomy for node-positive unilateral breast cancer in our institution between November 1, 2019 and February 28, 2021. To assess the effect of preventive ILR, we divided the patients into a treatment group (n=30) and a control group (n=183). Univariate and multivariate Cox proportional hazards regression models were used to evaluate the association between ILR and lymphedema occurrence.

Results:

Of the 30 patients who were attempted, we successfully performed ILRs in 26 patients (86.7%). During a mean follow-up of 14 months, one patient (3.8%) was confirmed to have upper extremity lymphedema in the treatment group, whereas 14 out of 183 patients (7.7%) were diagnosed in the control group. In multivariate analysis, ILR success showed a borderline significant decrease in risk of lymphedema [hazard ratio (HR) =0.174; 95% confidence interval (CI) 0.022-1.374; P=0.097].

Conclusions:

Our results suggested that ILR may be a promising surgical treatment to prevent postoperative lymphedema. There is a need for larger studies with longer follow-up to confirm the findings obtained in our study.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Gland Surg Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Gland Surg Año: 2023 Tipo del documento: Article