Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles.
Laryngoscope Investig Otolaryngol
; 8(2): 495-504, 2023 Apr.
Article
en En
| MEDLINE
| ID: mdl-37090882
ABSTRACT
Objectives:
Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans.Methods:
Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross-sectional analysis of 1106 Jackson Heart Study participants. Hearing loss was defined as puretone average (PTA0.5,1,2,4) > 15 dB HL. Distortion product otoacoustic emissions (DPOAEs) were collected for f 2 = 1.0-8.0 kHz. Two amplitude averages were computed DPOAElow (f 2 ≤ 4 kHz) and DPOAEhigh (f 2 ≥ 6 kHz). Based on major CVD risk factors (diabetes, current smoking, total cholesterol ≥240 mg/dL or treatment, and systolic blood pressure [BP]/diastolic BP ≥ 140/≥90 mmHg or treatment), four risk groups were created 0, 1, 2, and ≥3 risk factors. Logistic regression estimated the odds of hearing loss and absent/reduced DPOAElow and DPOAEhigh by CVD risk status adjusting for age, sex, education, BMI, vertigo, and noise exposure.Results:
With multivariable adjustment, diabetes was associated with hearing loss (OR = 1.48 [95% CI 1.04-2.10]). However, there was not a statistically significant relationship between CVD risk factors (individually or for overall risk) and DPOAEs.Conclusion:
Diabetes was associated with hearing loss. Neither individual CVD risk factors nor overall risk showed a relationship to cochlear dysfunction. Level of Evidence 2b.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Laryngoscope Investig Otolaryngol
Año:
2023
Tipo del documento:
Article