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Prodrug Strategies for the Development of ß-l-5-((E)-2-Bromovinyl)-1-((2S,4S)-2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l-BHDU) against Varicella Zoster Virus (VZV).
Singh, Uma S; Konreddy, Ananda K; Kothapalli, Yugandhar; Liu, Dongmei; Lloyd, Megan G; Annavarapu, Vidya; White, Catherine A; Bartlett, Michael G; Moffat, Jennifer F; Chu, Chung K.
Afiliación
  • Singh US; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • Konreddy AK; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • Kothapalli Y; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • Liu D; State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Lloyd MG; State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Annavarapu V; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • White CA; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • Bartlett MG; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
  • Moffat JF; State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Chu CK; Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.
J Med Chem ; 66(10): 7038-7053, 2023 05 25.
Article en En | MEDLINE | ID: mdl-37140467

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Profármacos / Dioxolanos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Profármacos / Dioxolanos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos