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[Immune function and research progress of pentraxin 3 in pulmonary infectious diseases].
Song, M Y; Gu, Y; Wang, J M; Liu, L L; Li, P; Su, X.
Afiliación
  • Song MY; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing 210002, China.
  • Gu Y; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing 210002, China.
  • Wang JM; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing 210002, China.
  • Liu LL; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
  • Li P; Department of Respiratory and Critical Care Medicine, Taikang Xianlin Drum Tower Hospital, Nanjing 210046, China.
  • Su X; Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing 210002, China.
Zhonghua Jie He He Hu Xi Za Zhi ; 46(5): 517-520, 2023 May 12.
Article en Zh | MEDLINE | ID: mdl-37147817
Pentraxins3 (PTX3) is an acute-phase protein of the pentraxin family that is synthetized and stored in a variety of cells. As an important mediator of innate immunity, PTX3 is rapidly released during microbial invasion and inflammatory response. It promotes the recognition of pathogens by myeloid cells through regulating complement activation. Recent studies have indicated that PTX3 concentrations in peripheral blood or tissues increase rapidly after infection, and the increased level is associated with the severity of the disease. Thus, PTX3 appears to be a vital clinical biomarker in the diagnosis and prognosis of pulmonary infectious diseases.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / Inflamación Límite: Humans Idioma: Zh Revista: Zhonghua Jie He He Hu Xi Za Zhi Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / Inflamación Límite: Humans Idioma: Zh Revista: Zhonghua Jie He He Hu Xi Za Zhi Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: China